| Baseball | Danny Hultzen | 2011 | John Olerud Two-Way Player Award |
| Tyler Wilson | 2011 | Lowe’s Senior CLASS Award |
| Men’s Basketball | Ralph Sampson | 1981 | Associated Press National Player of the Year |
| | | United Press International National Player of the Year |
| | | US Basketball Writers Association National Player of the Year |
| | | Basketball Times National Player of the Year |
| | | RUPP National Player of the Year |
| | 1982 | Associated Press National Player of the Year |
| | | United Press International National Player of the Year |
| | | US Basketball Writers Association National Player of the Year |
| | | Basketball Times National Player of the Year |
| | | RUPP National Player of the Year |
| | | Wooden Award National Player of the Year |
| | | Naismith National Player of the Year |
| | | NABC National Player of the Year |
| | | The Sports Network National Player of the Year |
| | | Co-Helms National Player of the Year |
| | 1983 | Associated Press National Player of the Year |
| | | United Press International National Player of the Year |
| | | US Basketball Writers Association National Player of the Year |
| | | Basketball Times National Player of the Year |
| | | RUPP National Player of the Year |
| | | Wooden Award National Player of the Year |
| | | Naismith National Player of the Year |
| | | NABC National Player of the Year |
| Malcolm Brogdon | 2016 | NABC National Defensive Player of the Year |
| Football | Bill Dudley | 1941 | Maxwell Award (Outstanding Player) |
| Heath Miller | 2004 | Mackey Award (Outstanding TE) |
| Chris Long | 2007 | Ted Hendricks Award (Outstanding DE) |
| Joe Reed | 2019 | Jet Award (Outstanding Specialist) |
| Men's Lacrosse | Gordon Jones | 1952 | Turnbull Award (Outstanding Attackman) |
| Deeley Nice | 1962 | Cone Award (Outstanding Goalie) |
| Pete Eldredge | 1972 | Enners Award (Outstanding Player) |
| Boo Smith | 1974 | Schmeisser Cup (Outstanding Defenseman) |
| Rodney Rullman | 1975 | Kelly Award (Outstanding Goalie) |
| John Driscoll | 1980 | MacLaughlin Award (Outstanding Midfielder) |
| Rick Guisto | 1982 | MacLaughlin Award (Outstanding Midfielder) |
| Steve Brnye | 1983 | Schmeisser Cup (Outstanding Defenseman) |
| Roddy Marino | 1986 | Turnbull Award (Outstanding Attackman) |
| Peter Sheehan | 1986 | Kelly Award (Outstanding Goalie) |
| Michael Watson | 1996 | Turnbull Award (Outstanding Attackman) |
| Doug Knight | 1996 | Enners Award (Outstanding Player) |
| Ryan Curtis | 1999 | Schmeisser Cup (Outstanding Defenseman) |
| Jay Jalbert | 1999 | MacLaughlin Award (Outstanding Midfielder) |
| Chris Rotelli | 2003 | Tewaaraton Trophy (Outstanding Player) |
| | | MacLaughlin Award (Outstanding Midfielder) |
| Tillman Johnson | 2003 | Enners Award (Outstanding Player) |
| | | Kelly Award (Outstanding Goalie) |
| Michael Culver | 2006 | Schmeisser Cup (Outstanding Defenseman) |
| Kyle Dixon | 2006 | MacLaughlin Award (Outstanding Midfielder) |
| Matt Ward | 2006 | Tewaaraton Trophy (Outstanding Player) |
| | | Enners Award (Outstanding Player) |
| Ken Clausen | 2010 | Schmeisser Cup (Outstanding Defenseman) |
| Steele Stanwick | 2011 | Tewaaraton Trophy (Outstanding Player) |
| | 2012 | Turnbull Award (Outstanding Attackman) |
| Ryan Conrad | 2019 | Senior CLASS Award |
| Jared Conners | 2021 | MacLaughlin Award (Outstanding Midfielder) |
| Matt Moore | 2022 | Senior CLASS Award |
| Men’s Soccer | John Harkes | 1987 | Missouri Athletic Club Player of the Year |
| Bob Willen | 1987 | adidas Goalkeeper of the Year |
| Tony Meola | 1989 | MAC Hermann Trophy |
| | | Missouri Athletic Club Player of the Year |
| Claudio Reyna | 1992 | Missouri Athletic Club Player of the Year |
| | | Soccer America Player of the Year |
| | 1993 | MAC Hermann Trophy |
| | | Missouri Athletic Club Player of the Year |
| | | Soccer America Player of the Year |
| | | Soccer News Player of the Year |
| AJ Wood | 1994 | Soccer America Player of the Year |
| Mike Fisher | 1995 | MAC Hermann Trophy |
| | | Soccer America Player of the Year |
| | 1996 | MAC Hermann Trophy |
| | | Missouri Athletic Club Player of the Year |
| | | NSCAA/United Soccer Coaches Player of the Year |
| Ben Olsen | 1997 | Soccer America Player of the Year |
| | | Soccer News Player of the Year |
| Alecko Eskandarian | 2002 | MAC Hermann Trophy |
| | | NSCAA/United Soccer Coaches Player of the Year |
| | | Soccer America Player of the Year |
| Joe Bell | 2019 | TopDrawerSoccer.com Player of the Year |
| Men’s Tennis | Somdev Devvarman | 2007 | ITA National Player of the Year |
| | 2008 | ITA National Player of the Year |
| Jarmere Jenkins | 2013 | ITA National Player of the Year |
| Wrestling | Scott Moore | 2004 | Gorriaran Trophy |
| Brent Jones | 2010 | Gorriaran Trophy |
| Women's Basketball | Dawn Staley | 1991 | Naismith Player of the Year |
| | | USBWA Player of the Year |
| | | Champion USA Player of the Year |
| | | WBCA Player of the Year |
| | | Sports Illustrated Player of the Year |
| | | Honda Sports Award |
| | 1992 | Naismith Player of the Year |
| | | USBWA Player of the Year |
| | | Champion USA Player of the Year |
| | | WBCA Player of the Year |
| Dena Evans | 1993 | Francis Pomeroy Naismith Player of the Year |
| Monica Wright | 2010 | WBCA Defensive Player of the Year |
| Women's Cross Country | Lesley Welch | 1983 | Honda Sports Award |
| Field Hockey | Peggy Boutilier | 1999 | NCAA Woman of the Year |
| Tara Vittese | 2015 | NFHCA National Player of the Year |
| | 2016 | NFHCA National Player of the Year |
| | 2017 | NFHCA National Player of the Year |
| Women's Lacrosse | Robyn Nye | 1991 | IWLCA National Player of the Year |
| | | IWLCA Defensive Player of the Year |
| Jenny Slingluff | 1992 | IWLCA National Player of the Year |
| | | IWLCA Offensive Player of the Year |
| Cherie Greer | 1994 | IWLCA National Player of the Year |
| | | IWLCA Defensive Player of the Year |
| Michelle Cusimano | 1995 | IWLCA National Player of the Year |
| | | IWLCA Goalkeeper of the Year |
| | 1996 | IWLCA National Player of the Year |
| | | IWLCA Goalkeeper of the Year |
| Peggy Boutilier | 1997 | IWLCA National Player of the Year |
| | | IWLCA Defensive Player of the Year |
| | 1998 | IWLCA National Player of the Year |
| | | IWLCA Defensive Player of the Year |
| | 1999 | NCAA Woman of the Year |
| Lauren Aumiller | 2002 | Inside Lacrosse Midfield Player of the Year |
| | 2003 | Inside Lacrosse Midfield Player of the Year |
| Amy Appelt | 2003 | Honda Sports Award |
| | 2004 | Inside Lacrosse Offensive Player of the Year |
| | | IWLCA National Player of the Year |
| | | IWLCA Offensive Player of the Year |
| | 2005 | Inside Lacrosse Offensive Player of the Year |
| Tiffany Schummer | 2003 | Inside Lacrosse Defensive Player of the Year |
| Nikki Lieb | 2006 | Defensive Midfielder National Player of the Year |
| Women's Soccer | Morgan Brian | 2013 | MAC Herman Trophy |
| | | Soccer America National Player of the Year |
| | | TopDrawerSoccer.com National Player of the Year |
| | 2014 | MAC Herman Trophy |
| Women's Swimming & Diving | Kate Douglass | 2022 | Honda Sports Award |
| | 2023 | Honda Sports Award |
| Women's Tennis | Danielle Collins | 2016 | Honda Sports Award |
